Asia-Pacific has shown important leadership on HIV/AIDS and has made solid progress towards controlling the epidemic in the region. In this op-ed, however, the authors draw attention to recent indicators suggesting that Asia has fallen behind in the fight against HIV/AIDS in key areas compared to other regions of the world. After summarising some of the obstacles to achieving epidemic control, such as widespread stigma and discrimination, the authors offer possible solutions for how the region can close gaps in HIV testing and treatment.