The SRN aims to prospectively capture and analyze standardized data among people living with HIV (PLWHIV) in care at IeDEA sites in low-middle income countries (LMICs). This network will implement studies on non-communicable diseases (NCDs) with a focus on cardiovascular risk factors, mental health, alcohol and other substance use, and liver disease across “sentinel” HIV clinics within the regions of the Asia-Pacific, the Caribbean, Central, South America, Central Africa, East Africa, Southern Africa, and West Africa.
- To establish a dedicated prospective cohort to study the epidemiology of NCDs and ageing among PLWHIV on antiretroviral therapy (ART).
- To describe the prevalence and factors associated with cardiovascular disease and metabolic syndrome among PLWHIV.
- To describe the prevalence of alcohol and other substance use, mental health issues (e.g., depression, anxiety), as well as their association with HIV treatment outcomes (e.g., presentation to care with advanced HIV, sustained HIV viral suppression).
- To describe the prevalence of liver fibrosis and liver steatosis among PLHIV and examine associated etiologic factors, including infectious and noninfectious conditions.
Antoine Jaquet, Bordeaux Population Health, INSERM1219, ISPED, Université de Bordeaux, Bordeaux, France
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